Binding of Matrix Metalloproteinase Inhibitors to Extracellular Matrix: 3D-QSAR Analysis
نویسندگان
چکیده
منابع مشابه
Two Matrix Metalloproteinase Inhibitors from Scrophularia Striata Boiss
Many species belonging to the Scrophularia genus have been used since ancient times as folk remedies for many medical conditions such as scrofulas, scabies, tumors, eczema, psoriasis, inflammations. The aim of this study was to characterize the matrix metalloproteinases (MMPs) inhibitor compounds of the Scrophularia striata extract by bio-guide fractionation. The aerial parts of S. striata were...
متن کاملTwo Matrix Metalloproteinase Inhibitors from Scrophularia Striata Boiss
Many species belonging to the Scrophularia genus have been used since ancient times as folk remedies for many medical conditions such as scrofulas, scabies, tumors, eczema, psoriasis, inflammations. The aim of this study was to characterize the matrix metalloproteinases (MMPs) inhibitor compounds of the Scrophularia striata extract by bio-guide fractionation. The aerial parts of S. striata were...
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Background and Aims: Despite patient’s demand increased for tooth color restorations, the stable bond between dentin and composite is a challenge in dentistry. Dentin protease activation is responsible for dentin-resin bond failure. The aim of this study was to determine the best pretreatment agent to inhibit matrix metalloproteinase and increase resin-dentin bond durability. Materials and Met...
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Some three-dimensional quantitative structure-activity relationship (3D-QSAR) models have been constructed using the comparative molecular field analysis (CoMFA) and comparative molecular similarity indices (CoMSIA) for a series of 84 proline-based plus 12 structurally more diversified nonproline matrix metalloproteinase inhibitors. The structures of these inhibitors were built from a structure...
متن کاملtwo matrix metalloproteinase inhibitors from scrophularia striata boiss
many species belonging to the scrophularia genus have been used since ancient times as folk remedies for many medical conditions such as scrofulas, scabies, tumors, eczema, psoriasis, inflammations. the aim of this study was to characterize the matrix metalloproteinases (mmps) inhibitor compounds of the scrophularia striata extract by bio-guide fractionation. the aerial parts of s. striata were...
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ژورنال
عنوان ژورنال: Chemical Biology & Drug Design
سال: 2008
ISSN: 1747-0277,1747-0285
DOI: 10.1111/j.1747-0285.2008.00710.x